Pain is perceived in the brain and the central nervous system but research suggests the immune system may play a role in conditions including fibromyalgia and chronic back pain

For years people with conditions such as fibromyalgia or bad back pain to name just two have been told the pain is all in their head. With no obvious physical symptoms, nociplastic pain can be difficult to diagnose but its effects are very, very real. Research suggests that the immune system plays a role in nociplastic pain, giving people ‘feel bad’ symptoms including fatigue, anxiety and nausea